Zoloft is one of the most prescribed antidepressants of the selective serotonin reuptake inhibitor (SSRI) class indicated for the treatment of major depression, obsessive-compulsive disorder (OCD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), panic disorder and social phobia (social anxiety disorder). Zoloft does not cause sedation and does not interfere with psychomotor performance.
Elavil is is a tricyclic antidepressant drug especially effective for the treatment of endogenous depression. It is also effective for pain relief in ankylosing spondylitis and is used as a preventive for patients with frequent/chronic migraines. It may also be used to treat nocturnal enuresis (bed wetting).